byMary-Sinclair, Michelle N.; Wang, XiaoFei; Swanson, Douglas J.; Sung, Caroline Y.; Mendonca, Eneida A.; Wroblewski, Kristen; Baumer, Shannon H.; Goldowitz, Dan; Jablonski, Monica M.; Skapek, Stephen X.
This article is from Molecular Vision , volume 20 . Abstract Purpose: Persistent hyperplastic primary vitreous (PHPV) represents a developmental eye disease known to have diverse manifestations ranging from a trivial remnant of hyaloid vessels to a dense fibrovascular mass causing lens opacity and retinal detachment. PHPV can be modeled in mice lacking individual genes, but certain features of such models differ from the clinical realm. For example, mice lacking the Arf gene have uniformly... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945809
This article is from Molecular Vision , volume 19 . Abstract Purpose: In the present work, the aim was to systematically review all studies about the association of vascular endothelial growth factor A (VEGF-A) polymorphisms with age-related macular degeneration (AMD) and to perform a meta-analysis. Methods: Relevant studies were searched using PubMed, Embase, Wanfang (Chinese), VIP (Chinese), and the Chinese National Knowledge Infrastructure databases up to October, 2011. A meta-analysis was... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675058
This article is from Molecular Vision , volume 17 . Abstract Purpose: Visible light has been previously demonstrated to induce retinal ganglion cell (RGC)-5 cell death through the mitochondrial pathway. The present study was designed to determine whether visible light might also directly trigger the death pathway by damaging nuclear DNA. Methods: RGC-5 cells were exposed to various intensities and durations of visible light exposure. Cell viability and death were monitored with the... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244485